MicroRNA-21 is a potential link between non-alcoholic fatty liver disease and hepatocellular carcinoma via modulation of the HBP1-p53-Srebp1c pathway
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چکیده
منابع مشابه
MicroRNA-21 is a potential link between non-alcoholic fatty liver disease and hepatocellular carcinoma via modulation of the HBP1-p53-Srebp1c pathway
BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is a major risk factor for hepatocellular carcinoma (HCC). However, the mechanistic pathways that link both disorders are essentially unknown. OBJECTIVE Our study was designed to investigate the role of microRNA-21 in the pathogenesis of NAFLD and its potential involvement in HCC. METHODS Wildtype mice maintained on a high fat diet (HFD) ...
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ژورنال
عنوان ژورنال: Gut
سال: 2015
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gutjnl-2014-308430